全文获取类型
收费全文 | 1974篇 |
免费 | 304篇 |
国内免费 | 314篇 |
专业分类
化学 | 1495篇 |
晶体学 | 15篇 |
力学 | 244篇 |
综合类 | 31篇 |
数学 | 144篇 |
物理学 | 663篇 |
出版年
2024年 | 2篇 |
2023年 | 28篇 |
2022年 | 53篇 |
2021年 | 110篇 |
2020年 | 94篇 |
2019年 | 61篇 |
2018年 | 66篇 |
2017年 | 70篇 |
2016年 | 91篇 |
2015年 | 80篇 |
2014年 | 88篇 |
2013年 | 149篇 |
2012年 | 93篇 |
2011年 | 110篇 |
2010年 | 94篇 |
2009年 | 87篇 |
2008年 | 95篇 |
2007年 | 107篇 |
2006年 | 103篇 |
2005年 | 104篇 |
2004年 | 115篇 |
2003年 | 93篇 |
2002年 | 82篇 |
2001年 | 73篇 |
2000年 | 82篇 |
1999年 | 75篇 |
1998年 | 69篇 |
1997年 | 46篇 |
1996年 | 38篇 |
1995年 | 31篇 |
1994年 | 29篇 |
1993年 | 43篇 |
1992年 | 22篇 |
1991年 | 18篇 |
1990年 | 17篇 |
1989年 | 8篇 |
1988年 | 12篇 |
1987年 | 7篇 |
1986年 | 8篇 |
1985年 | 6篇 |
1984年 | 6篇 |
1983年 | 2篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 5篇 |
1979年 | 1篇 |
1975年 | 2篇 |
1972年 | 1篇 |
1966年 | 1篇 |
1957年 | 2篇 |
排序方式: 共有2592条查询结果,搜索用时 15 毫秒
1.
蛋白质-多糖复合体系作为生物活性物质传递系统的壁材,有着人工合成聚合物或无机物等其他材料不可比拟的多重优势。本文就蛋白质和多糖之间的连接方式及蛋白质-多糖复合体系形成传递系统的多种形式进行了综述,以及对此领域的发展趋势进行了展望。结合蛋白质和多糖的结构特点,二者之间的链接方式分为非共价结合的物理共聚,和共价结合的美拉德偶联、化学交联、酶催化交联等方式,文中分别对各种连接方式的原理和机理,以及其影响因素做了深入阐述。以蛋白质-多糖复合体系为壁材对活性物质的传递形式大体上分成乳化系统、胶束、纳米凝胶、分子复合物以及壳核结构等系统。不同的活性物质的特征和传递需求,可针对性地选择合适结构的蛋白质和多糖种类以及二者的连接方式和传递系统的形式。并且,随着研究的逐步发展和推进,此领域的发展趋势朝着智能化和靶向性的方向进行。目前活性物质的蛋白质-多糖复合体系的传递系统,还依然面临着系统设计、评价和应用等多方面的挑战,这就要求我们在更全面更深入了解认识其对活性物质影响和功效的基础上,安全合理地设计和深入细致地评价活性成分的传递系统。 相似文献
2.
3.
Hejia Hu Linlin Wu Mei Li Cun Xue Guangcheng Wang Siying Chen Yong Huang Lin Zheng Aimin Wang Yueting Li Zipeng Gong 《Biomedical chromatography : BMC》2020,34(1):e4714
Eucommia ulmoides Oliv. (E. ulmoides) is a valuable and nourishing medicinal herb in China that has been used in the treatment of hypertension. Given the fact that most traditional Chinese medicine is mainly used to treat disease, investigating the pharmacokinetics of traditional Chinese medicines in the pathological state is more useful than that in the normal state. However, the differences in the absorption kinetics of active ingredients of E. ulmoides extract between pathological and physiological conditions have not been reported. Therefore, in this study, the rat intestinal in situ circulatory perfusion model was used to investigate the differences in absorption kinetics of seven active ingredients of E. ulmoides extract in normal and spontaneously hypertensive rats, namely, genipinic acid, protocatechuic acid, neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, (+)-pinoresinol di-O-β-D -glucopyranoside and (+)-pinoresinol 4′-O-β-D -glucopyranoside. Our results indicate that the pathological state of spontaneous hypertension may change the absorption of active components of E. ulmoides extracts, and these findings may provide a reference for improving the rational use of E. ulmoides in the clinic. 相似文献
4.
R. J. Saykally K. M. Evenson D. A. Jennings L. R. Zink A. Scalabrin 《International Journal of Infrared and Millimeter Waves》1987,8(6):653-662
Twenty new cw FIR laser lines in CD3OH, optically pumped by a CO2 laser, are reported. The frequencies of 39 of the stronger laser lines were measured relative to stabilized CO2 lasers with a fractional uncertainty, as determined by the reproducibility of the FIR frequency itself, of 2 parts in 107.Contribution of the U.S. Government, not subject to copyright. 相似文献
5.
从现行典型园区网络安全设计方案入手,结合其在安全防范解决方案上存在的问题,提出了一种网络主动安全模型;在全局网络安全认识的基础上.阐述了模型组成部件的功能定义和网络主动安全实现流程;采用统一网络入口认证、网络知识发现及资源有效控制、沟通等手段,解决了现行网络安全设计中存在的恶意攻击行为源头定位困难,以及信息安全司法取证不准、网络资源安全被动防护、网络灾难快速反映能力差等问题.实验结果表明,该设计方案具有较好的可行性和实用性. 相似文献
6.
The basic concepts about the active structures and some attributes of the modes were presented in paper "Liner Active Structures and Modes ( Ⅰ ) ". The characteristics of the active discrete systems and active beams were discussed, especially, the stability of the active structures and the orthogonality of the eigenvectors. The notes about modes were portrayed by a model of a seven-storeyed building with sensors and actuators. The concept of the adjoint active structure was extended from the discrete systems to the beams that were the representations of the continuous structures. Two types of beams with different placements of the measuring and actuating systems were discussed in detail. One is the beam with the discrete sensors and actuators, and the other is the beam with distributed sensor and actuator function. The orthogonality conditions were derived with the modal shapes of the active beam and its adjoint active beam. An example shows that the variation of eigenvalues with feedback amplitude for the homo-configuration and non-homo-configuration active structures. 相似文献
7.
Marco Sangermano Mehmet Atilla Tasdelen Yusuf Yagci 《Journal of polymer science. Part A, Polymer chemistry》2007,45(21):4914-4920
Photoinitiated cationic polymerization of mono‐ and bifunctional epoxy monomers, namely cyclohexeneoxide (CHO), 4‐epoxycyclohexylmethyl‐3′,4′‐epoxycyclohexanecarboxylate (EEC), respectively by using sulphonium salts in the presence of hydroxylbutyl vinyl ether (HBVE) was studied. The real‐time FTIR spectroscopic, gel content determination, and thermal characterization studies revealed that both hydroxyl and vinyl ether functionalities of HBVE take part in the polymerization. During the polymerization, HBVE has the ability to react via both active chain end (ACE) and activated monomer mechanisms through its hydroxyl and vinyl ether functionalities, respectively. Thus, more efficient curing was observed with the addition of HBVE into EEC‐containing formulations. It was also demonstrated that HBVE is effective in facilitating the photoinduced crosslinking of monofunctional epoxy monomer, CHO in the absence of a conventional crosslinker. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 4914–4920, 2007 相似文献
8.
9.
Leonard M Khalilov Ludmila V Parfenova Askhat G Ibragimov Usein M Dzhemilev 《Journal of organometallic chemistry》2004,689(2):444-453
This paper is dedicated to a study of properties of the following novel optically active organoaluminium compounds (OACs): (1S,2S)-l,7,7-trimethyl-2-[(dialkylalumina)oxy]-bicyclo[2.2.1]heptanes and (1S)-N-(dialkylalumina)-6,7-dimethoxy-1-methyl-1,2,3,4- tetrahydroisoquinolines. The synthesis of the chiral OACs was carried out in the reaction of either natural camphor or salsolidine with both AlEt3 and i-Bu2AlH. The main goal of the research was to investigate the stereodifferentiating activity of the chiral OACs in the olefin carbo- and cycloalumination reactions, catalyzed by Cp2ZrCl2. 相似文献
10.
本文利用一个新的分片线性NCP函数提出一个新的可行的QP-free方法解非线性不等式约束优化问题.不同于其他的QP-free方法,这个方法只考虑在工作集中的约束函数,工作集是积极集的一个估计,因此子问题的维数不是满秩的.这个方法可行的并且不需假定严格互补条件、聚点的孤立性得到算法的全局收敛性,并且积极约束函数的梯度不要求线性独立的,其中由拟牛顿法得到的子矩阵不需要求一致正定性. 相似文献